Fatigue is a prevalent symptom in work settings and often found in the older population. It negatively impacts the quality of life and associates with elevated mortality rates in the older population. In addition, cognitive dysfunction is another important intrinsic factor of fall accidents. This study is aimed to examine effects of fatigue, induced by a laboratory-based fatigue protocol or an occupational activity, on balance control, cognitive performance, and their interaction. We will validate the use of whole-body fatigue protocol, establish biomechanical parameters used to indicate fatigue-induced balance deficits, compare these parameters before and after work in older male and female workers, and lastly, seek to establish a connection between differences in parameters and mechanisms induced by the laboratory-based fatigue protocol and occupational activity. Project outcome will identify the impact of fatigue as a risk factor for movement-related accidents, form a solid basis for future studies examining how biomechanical screening and assessment may preemptively identify individuals at risk, and help develop effective interventions to prevent fatigue-related injuries.